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Dr. Waras Nurcholis, MSi
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INDONESIA
Jurnal Jamu Indonesia
Published by Institut Pertanian Bogor
ISSN : 24077178     EISSN : 24077763     DOI : 10.29244
Core Subject : Education, Agriculture,
Agriculture, Biological Sciences & Forestry Other
Jurnal Jamu Indonesia (JJI) didedikasikan untuk pertukaran informasi dan pemahaman keilmuan yang meluas mengenai pengembangan dunia jamu melalui penerbitan makalah-makalah Ilmiah. Tema makalah ilmiah yang menjadi lingkup JJI meliputi tema riset jamu dari hulu kehilir yang tidak terbatas pada riset etnobotani dan pengetahuan lokal, eksplorasi, Konservasi, Domestikasi sumberdaya hayati terkait jamu, pemuliaan varietas, pengembangan Good Agricultural and Collection Practices (GACP) bahan baku jamu, pengembangan standar bahan baku dan produk jamu, pengembangan produk jamu, Identifikasi senyawa aktif serta sintesisnya, Mekanisme kerja bioaktivitas formula jamu, aspek sosial dan ekonomi terkait dengan pengembangan jamu.
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Articles 6 Documents
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Search results for , issue "Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia" : 6 Documents clear
The Isolation and Identification of Active Compound of Dendrophthoe praelonga (Blume) Miq. Extract Against Breast Cancer Cells (MCF-7) M Irfan Junedi Irfan; Hendig Winarno; M Hanafi; Nina Artanti
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.117

Abstract

Petai mistletoe (Dendrophthoe praelonga (Blume) Miq) is semi-parasitic plant. Parasite plant has been used traditionally in Indonesia to prevent or treat degenerative diseases, such as cancer. The purpose of this study was to indentify anticancer compound of petai mistletoe leaves extract and to examine its antioxidant activity (based on DPPH method) and cytotoxic activity on breast cancer (MCF-7) cell lines in vitro using Alamar blue method. This research aims to isolating, characterize, determine antioxidant activity and cytotoxic activity. Separation was conducting column chromathography and characterize was conducted using TLC, FT-IR, LC-MS and NMR-1D. From the result obtained, the isolated compound is flavonol quercetine (3,3,7,3’,4’ pethahydroxyflavone) which active antioxidant with IC50 value of 9.4 μg/mL and the value of cytotoxic activity with IC50 750.62 μg/mL
Anti-allergic Activity of 70% Ethanol Extract of Strawberries in Ovalbumin Induced Male Mice Siska; Diene Roufiani; Ema Dewanti
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.167

Abstract

Anaphylaxis is the most common allergic reaction triggered by allergens such as insect poisons, food, and drugs through skin contact, injection, or inhalation. In vitro previous research showed that strawberries fruit have activity as antioxidant, anticancer, anti-inflammation, and anti-allergic. The research aimed to determine the antianaphylaxis strawberry fruit extract in mice (Balb/C strain) with ovalbumin-induced. Twenty-four Balb/C strain mice were divided into six groups (n=4). Group I and II as a normal and control group. Group III till VI as a treatment group was given cetirizine dose 0.042 mg/20 g BW and strawberry extract doses 0,68; 1,36; and 2,72 mg/20 g BW, respectively. This research showed that 70 % of ethanol extract of strawberries fruit have antiallergic activity in response to active cutaneous anaphylaxis. 70% ethanol extract of strawberries doses 2.72 mg/20 g BW had similar antiallergic activity compare with cetirizine. The conclusion of this study showed that strawberries fruit extract could be developed as an alternative medicine to anti-anaphylaxis or anti-allergic.
In Silico Analysis of Antiviral Activity of Analog Curcumin Compounds Esti Mulatsari; Titiek Martati; Esti Mumpuni; Nidya Luciana Dewi
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.173

Abstract

Some studies state that curcumin analog compounds can improve the bioavailability and biological activity of curcumin. One of the methods to predict the bioactivity of curcumin was computational using molecular docking method. This study has done bioactivity tests of curcumin analog compounds as antiviral using the molecular docking method with the software used are PLANTS, YASARA, MarvinSketch, and Pymol for visualization. This study used analog curcumin compounds derived from previous research. This study used five different viral reseptor types. The maraviroc, docosanol, ribavirin, and zanamivir were used as compound control in this research. The validated target protein consists of 5 (five) receptors with PDB codes 1V2I, 4WEG, 2HWI, 2QAD, and 3ALP. Based on this research, compounds that are predicted active as antiviral on each receptors that are: 2,5-bis(3,5-ditertbutyl-4-hydroxy benzyl)cyclopentanone (1V2I), 1,7- diphenyl-1,6-heptadiene-3,5-dione (4WEG), 1,7-bis(3,4-dibenzyloxiphenyl)-1,6-heptadiene-3,5-dione (2HWI), and 2,5-bis(3,5-ditertbutyl-4-hydroxybenzyl)cyclopentanone (3ALP).
Effect of Seaweed Ethanol Extract on Cholesterol Levels and Obesity in White Rats Magfirah; Indah Kurnia Utami; Syafika Alaydrus
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.175

Abstract

Seaweed (EucheumaCottonii J. Agardh) is one of the biological resources found in coastal and marine areas. Seaweed contains secondary metabolites such as flavonoids, alkaloids, polyphenols and tannins which can reduce cholesterol levels in the blood. This study aims to determine the effect of seaweed ethanol extract on reducing cholesterol and obesity levels by comparing plasma cholesterol levels, body weight, and weight of vital organs (liver, kidneys and jantumg) of obese rats, mice given seaweed ethanol extract with normal mice . Rats were grouped randomly into 6 groups. group one was given 0.5% CMC Na, group two was given high fat diet food, group three was given simvastatin, group four was given seaweed ethanol extract 100 mg / kgbb, group five was given ethanol extract of seaweed 200 mg / kgbb and group six was given ethanol extract of seaweed 300 mg / kg with a long suspension of extract for 14 days. Measurement of cholesterol levels in the blood using the CHOD-PAP method, body weight and organs carried out by weighing. The results showed that seaweed ethanol extract has the effect of inhibiting an increase in plasma cholesterol levels and has anti-obesity potential at a dose of 300 mg / kgbb.
Profile of Micro, Small, and Medium Industrial Herbal Medicine Products in Sukoharjo Regency Irmanida Batubara; Ninuk Purnaningsih; Titi Mawasti
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.186

Abstract

Sukoharjo is one of the districts in Central Java that has a large number of herbal medicine entrepreneurs, including many small and medium industries. This small and medium industry needs to improve the quality of product safety. Therefore, this study aims to obtain the profile of small and medium industry herbal medicine products in Sukoharjo Regency. A total of 6 types of products (candy (1), mixture (3), extract (1), and tea (1)) were collected and the uniform weights, water content, organoleptic, hazardous metal content and microbiological safety were determined. The results showed that the product had fulfilled the water content, lead, cadmium, and arsenic content, and fulfilled the requirements of total plate count (TPC), coliform, and yeast mold. Product quality still needs to be improved in terms of uniformity of weight and packaging labels. The conclusion of this research is the profile of small and medium industry products in Sukoharjo Regency has met safety requirements but needs to be improved in quality.
RETRACTION NOTICE TO: Uji Aktivitas Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Agen Anti-Katarak Eny Kusrini; Dewi Tristantini; Ni’matul Izza
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika LPPM IPB; Tropical Biopharmaca Research Center - Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.225

Abstract

​Artikel dengan judul Uji Aktivitas Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Agen Anti-Katarak telah dilakukan pencabutan dari Jurnal Jamu Indonesia Vol. 2 No. 1 (2017), pada tautan daring http://jamu.journal.ipb.ac.id/index.php/JJI/article/view/28.Pencabutan artikel dilakukan karena permintaan author.Pemberitahuan pencabutan dari artikel tersebut dapat ditemukan pada http://jamu.journal.ipb.ac.id/index.php/JJI/article/view/225.

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